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Research and Development / Histology
Histology is the study of biological material and the ways in which its components interact, both structurally and functionally.
 
The Three-Dimensional Architectural Structure of the Micro-Macro Porous Biphasic HA and TCP Bioceramic is shown below.
 
Scaffold Surface Topography

 

Histological Aspects of the Behavior of the Micro-Macro Porous Calcium Phosphate
Bioceramic on Bone Tissue are shown below
 

 

Histomorphometry

Histomorphometry is the only method capable of giving us direct, precise analytical access to the cell activity
and the tissue remodeling mechanisms involved in the physiotherapy of osteoporosis and in the correct
response of the bone mass to the therapy applied.

 

Statistical Analysis - Kruskal, Wallis

HISTOLOGY

Sham (Control)


Cortex Marrow
Original magnified 250x Original magnified 500x

WITH NO RECONSTRUCTION


  15 days 30 days 90 days
  250 x 500 x 250 x

  500 x 500 x 500 x



BIOCERAMIC


  15 days 30 days 90 days
  1000 x 500 x 500 x

  250 x 500 x 500 x


Histomorphometric Analysis



Averages of the different sacrifice periods with different variables
in the cortical and medullary regions, in the Sham Group



Averages of the different sacrifice periods with different variables
in the cortical and medullary regions, in the With No Reconstruction Group



Averages of the different sacrifice periods with different variables
in the cortical and medullary regions, in the Bioceramic Group

 

Osteointegration and bone tissue neoformation

Material in Blocks Material in Granules



   


In Vivo demonstration of results in humans

 
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